Why choose Cocoon Bioscience as your recombinant protein provider
When it comes to selecting a recombinant protein provider, there are countless factors to consider. From the quality of the protein to the provider’s expertise, every element plays a crucial role in your research or product development.
At Cocoon, we offer an unparalleled dedication to innovation and performance. Our unique platform enables us to deliver a comprehensive suite of solutions designed to meet the specific needs of various industries, including life science research, biopharmaceuticals, cell culture, and more.
In this blog, we dive deeper into how recombinant protein providers differ, and what makes Cocoon Bioscience stand out.
The importance of choosing the right recombinant protein provider
In the complex world of biotechnology and life sciences, the choice of a recombinant protein provider can make or break your project. The quality, cost, consistency, purity, and performance of recombinant protein products are non-negotiable elements that directly impact your results. However, how your partner collaborates with you also matters. The processes they use can significantly impact the logistics and efficacy of your project.
For example, how long is their development roadmap? How much customization do they support? What kind of yields do they produce, and how easily can this be scaled up or down? These are all parameters which can impact how your research or development project runs.
This is why partnering with a provider like Cocoon, known for its unwavering commitment to these standards, is vital.
We aren’t just another player in the recombinant protein space; we’re a leader in providing high-performance, complex proteins, such as specialty enzymes and growth factors at highly cost-effective rates. All the while, we consistently meet or exceed industry standards. Whether you’re working on mRNA production, gene sequencing, or even regenerative medicine, Cocoon’s offerings are tailor-made to fit these niche, yet crucial, applications.
Cocoon’s expertise: what sets us apart
Our platform
Developed over nearly two decades, our CrisBio® platform leverages a unique technology. With an automated platform that utilizes insect cocoons as natural bioreactors, we achieve high expression rates and can often express ‘impossible’ enzymes which traditional systems fail to do. What’s more, our advanced expression systems maximize protein quality while ensuring scalability and efficiency.
Our platform can produce a wide range of complex proteins, growth factors and enzymes that traditional systems have struggled to achieve. Moreover, we can produce them with consistency, reliability and according to your specifications.
Our expertise
When it comes to recombinant proteins, our expertise is everything. Our team of experts collaborates closely with you to ensure that the final product aligns perfectly with your specific project needs. Our deep knowledge and hands-on approach become especially crucial when timelines are tight, and quality output is so important.
Why choose Cocoon for recombinant proteins?
1. Speed meets quality
Time is often a critical factor in biotechnology and pharmaceutical research. At Cocoon, we understand that fast lead times can be a game-changer for our clients. That’s why we’ve developed a rapid development funnel that allows us to quickly move from concept to production.
We have a complete product portfolio of growth factors, and, for custom development, it takes just three months to produce a proof-of-concept.
The speed of our development is further supported by our high rates of successful expression. Using a multi-cellular approach and the CrisBio® platform, we outperform a single cell approach. In other words, the use of whole organisms ensures our production is efficient, fast and reliable.
That being said, we never sacrifice quality in our production. Our 5-stage process balances speed and quality, ensuring every batch is created with efficiency then rigorously tested to ensure it meets the right standards:
- Pupae production: our insect rearing workflow is designed to support the entire life cycle of the insects within our facilities.
- Master and working virus generation: baculovirus (BEVS), a virus harmless to humans and animals, is engineered with the desired gene in its DNA to trigger production of the target protein within the insect.
- Upstream process: chrysalises are inoculated with the designated virus through an automated process, resulting in the replication of the virus within the insect to produce the desired protein.
- Downstream process: industry-standard techniques are employed to extract and purify the protein of interest from the cocoon and insect mass.
- Fill & finish: stringent quality control is implemented to ensure sterility, accurate measurement, correct sealing, and appropriate labeling.
2. Customization at its best
One of our standout features at Cocoon is our customization capabilities. We understand that each project is unique, and a one-size-fits-all approach doesn’t cut it in the life sciences industry. That’s why we offer bespoke solutions, from custom enzyme development to specialized recombinant proteins tailored to your specific needs.
Whether you’re working in cell culture, biopharmaceuticals, or regenerative medicine, our team works closely with you to develop solutions that perfectly align with your objectives. This level of customization ensures that you’re not just getting a product; you’re getting a solution designed to maximize your success.
3. Performance
Our proteins and enzymes are expressed within the multi-cellular environment of the insect, which naturally handles complex folding and post-translational modifications. The results are enzymes and proteins that meet the activity of commercially available gold standards. This multi-cellular approach, facilitated by our insect cocoons, enhances the functionality and reliability of the proteins we produce.
4. High biosafety
By excluding mammalian components, our technology ensures high biosafety, eliminating the possibility of cross-contamination. This approach not only ensures that our products are safe for use across various applications but also aligns with the regulatory requirements of industries like biopharmaceuticals and life sciences.
5. Unmatched technical assistance
In addition to our high-quality products, we at Cocoon are proud to offer unparalleled technical assistance to our clients. We understand that the successful application of recombinant proteins often requires more than just a good product—it requires expert guidance and support.
Our team is available to assist you at every stage of your project, from when we receive the gene sequence to troubleshooting and optimization. This level of support ensures that you can confidently move forward with your research or product development, knowing that you have a team of experts backing you up.
6. Cost-effectiveness without compromise
At Cocoon, cost-effectiveness doesn’t come at the expense of quality. Thanks to our use of insect cocoons as natural bioreactors, we eliminate the need for resource-heavy bioreactors, reduce material requirements, and optimize output yield and performance. Our automated platform and innovative approach makes our process more affordable. But, it also ensures that our end products are accessible for our clients.
This commitment to cost-effectiveness makes Cocoon an ideal partner for companies looking to maximize their budgets while still getting the best possible products. So, whether you’re a startup in the life sciences industry or an established player, Cocoon offers solutions that deliver both value and quality.
Cocoon’s offerings as a recombinant protein provider
At Cocoon, our offerings are tailored to meet the demands of various industries. Our focus is on delivering high-quality recombinant growth factors and recombinant specialty enzymes that drive innovation and efficiency in your R&D processes.
The role of growth factors
Cocoon’s portfolio of growth factor products is a testament to our commitment to serving a broad range of industries. Growth factors play a pivotal role in cell culture, especially in emerging fields like cultivated meat and tissue engineering. Our growth factors are not only high-quality but also optimized for consistency and reproducibility. This ensures that your cell cultures thrive under optimal conditions.
In the biopharmaceutical industry, growth factors are crucial for the development of innovative therapies and drugs. As a result, Cocoon’s offerings are designed to meet the rigorous demands of this highly regulated industry.
We offer established products like FGF-2 Bovine or Human, as well as solutions like TGF-β1 which is under development.
Explore our growth factors portfolio
The role of recombinant enzymes
In addition to growth factors, Cocoon is a recombinant protein provider that excels in the development and provision of recombinant enzymes. These enzymes are critical in numerous life sciences applications, particularly in mRNA production and gene sequencing. Our recombinant enzymes are designed for high specificity and activity, ensuring that your processes are efficient and reliable.
We work with companies conducting research in gene editing or working on next-generation sequencing technologies. Either way, Cocoon’s recombinant enzymes provide the performance and reliability you need.
