Using cocoons as natural bioreactors contributes to significant cost savings compared to traditional expression systems making it more financially accessible.
By excluding mammalian components, our technology ensures high biosafety, eliminating the possibility of cross-contamination.
We use non-genetically modified organisms, ensuring that the cells involved are also not genetically modified, providing a smooth route for regulatory approval.
Basic Fibroblast Growth Factor, known as FGF basic or FGF-2, is a member of the fibroblast growth factor FGF family.
FGF-2 controls fundamental biological processes, including cell growth and differentiation, tissue formation, tissue repair and angiogenesis. It’s commonly used as an ingredient for serum-free culture media for cultivated meat, cell culture applications, and for veterinary research applications.
Basic Fibroblast Growth Factor, known as FGF basic or FGF-2, is a member of the fibroblast growth factor FGF family.
FGF-2 is commonly used to support the maintenance of human embryonic stem cells and the proliferation and differentiation of induced pluripotent and mesenchymal stem cells. It’s a component used in tissue engineering constructs and cellular agriculture.
Epidermal Growth Factor, known as EGF, is a single polypeptide found in the human body.
It stimulates the growth of various epidermal and epithelial cells in vivo and in vitro, and of some fibroblasts in cell culture. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing.
Platelet-derived Growth Factor, known as PDGF, is a member of the platelet-derived growth factor family.
It’s a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue, and it plays a key role in embryonic development, cell proliferation, cell migration, and angiogenesis. Porcine PDGF consists primarily of PDGF homodimers and it has approximately 70-80% homology with the B-chain of human PDGF. Human and porcine PDGF bind to the same receptors and produce the same spectrum of biological effects.
Platelet-derived growth factor, known as PDGF, refers to a family of dimeric isoforms that have an effect on connective tissue cells, as well as on other types of cells.
It affects the differentiation of specific cell types and promotes cell survival. Through these effects, PDGF has important functions in certain organs during embryonic development, as well as in the adult stage in the stimulation of wound healing and in the maintenance of connective tissue homeostasis.
Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines.
In the context of cell agriculture for cultivated meat production, TGF-B1 can be used in vitro to stimulate the growth and differentiation of muscle and fat cells in culture.
Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines.
It has a crucial role in embryonic development, in regulating adult tissue homeostasis, and is a key regulator of physiological and pathological tissue repair responses. As well, TGF-β1 is an important cell differentiation, survival, proliferation, and behavior-inducing signalling molecule in all these conditions.
Cocoon’s growth factors are versatile and suitable for GMP-grade or food-grade production, meeting the demands of various industries like cellular agriculture, biopharmaceutical production and cosmetics.
In cellular agriculture, the growth factors stimulate cell proliferation and differentiation for sustainable and efficient food production.
Our growth factors can be used in pharmaceutical and biomedical applications for tissue engineering, wound healing, and regenerative medicine.
In cosmetics, growth factors stimulate collagen production, promote skin regeneration, and improve elasticity.